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Despite the frequency of UTIs, there is confusion about diagnostic strategies, and changes in antimicrobial resistance among uropathogens require alterations in traditional treatment regimens. The purpose of this bulletin is to address the diagnosis, treatment, and prevention of uncomplicated acute bacterial cystitis and acute bacterial pyelonephritis in nonpregnant women. Patients with acute pyelonephritis should complete days of total antimicrobial therapy, regardless of whether treatment is on an inpatient or outpatient basis level of evidence, A. Nitrofurantoin macrocrystals to mg times daily for days, or nitrofurantoin monohydrate mg twice daily for days. When resistance rates are more than to, antibiotic class should be changed. The material presented here does not necessarily reflect the views of Medscape or companies that support educational programming on www.

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